What REVIA is used for
REVIA is used to help opiate drug addicts discontinue their habit. It is also used to help alcoholics dry out and remain abstinent. Your doctor may have prescribed REVIA for another use. Ask your doctor if you have any questions about why REVIA was prescribed for you.
REVIA is not addictive. This medicine is available only with a doctor's prescription.

How REVIA works
REVIA tablets contain the active ingredient, naltrexone hydrochloride. It is an opiate antagonist. This means it fights the effects of opiate drugs (such as heroin) on the body, and blocks euphoria (or "high") due to these opiates.
The use of REVIA to treat your condition can lead to side-effects, which are discussed below.

Before you take REVIA
REVIA is not suitable for everyone.

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When you must not take REVIA:
You must not take REVIA if you have a history of severe allergic reactions to REVIA or to any of the ingredients listed at the end of this leaflet.
Do not take REVIA if you are still using heroin or drugs like it.
If you take REVIA right after taking an opiate you will suffer withdrawal symptoms (cold turkey) (such as nausea, vomiting, shakiness, sweating and anxiety) which may be severe.
Do not take REVIA if you are experiencing withdrawal symptoms.
Do not take REVIA if you are on certain pain killers. Ask your doctor or pharmacist.
Do not take REVIA if you have hepatitis or liver failure. Hepatitis is liver disease with nausea, vomiting, loss of appetite, feeling generally unwell, fever, itching, yellowing of the skin and eyes, and dark coloured urine.
Do not take REVIA after the expiry date printed on the pack. If you take this medicine after the expiry date has passed, it may not work as well.
Do not take REVIA if the packaging is torn or shows signs of tampering.

Before you take REVIA
Tell your doctor if you have allergies to:
any other medicines
any other substances, such as foods, preservatives or dyes.
Tell your doctor if you have or have had any medical conditions, especially the following:
Tell your doctor if you are pregnant or intend to become pregnant.
Tell your doctor if you are breastfeeding or intend to breastfeed.
Tell your doctor if you have or have had any liver disease.
Tell your doctor if you have or have had any kidney disease.
Tell your doctor if you are under 18 years of age.

Opioid Dependence

Indicated for the prevention of relapse to opioid dependence following opioid detoxification

Initial 25 mg PO, observe for 1 hr, THEN 50 mg PO qDay starting next day (flexible dosing regimens can be used to accomodate patient convenience or ensure compliance)

IM (Vivitrol): 380 mg IM q4Weeks in gluteal muscle only for maintenance of abstinence

ONLY USE after patient has been opioid free for 7-10 days and after negative naloxone challenge (no symptom withdrawal after naloxone administration)